New synthetic bone graft tested against donor tissue in spine surgery
NCT ID NCT05037968
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two bone graft materials used in spine fusion surgery for patients with degenerative disc disease and back or leg pain. One is a synthetic material called MagnetOs Flex Matrix, and the other is a donor-based graft called Trinity Elite. About 100 adults will be randomly assigned to receive one of the two grafts during surgery, and doctors will check how well the bones fuse using CT scans and X-rays over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MagnetOs Flex Matrix (synthetic bone graft) and Trinity Elite (donor bone graft)
What this could lead to
If successful, this study could show that a synthetic bone graft works as well as a donor-based graft for spine fusion, offering a reliable alternative.
What could go wrong
This is a small, early-phase study with only 100 participants. Results may not apply to all patients, and there is always a risk that the synthetic graft may not fuse bones as effectively.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hartford Hospital
RECRUITINGHartford, Connecticut, 06106, United States
Contact
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Huntsman Spinal Clinic
RECRUITINGSalt Lake City, Utah, 84124, United States
Contact
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Inova Healthcare
RECRUITINGFairfax, Virginia, 22031, United States
Contact
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MedStar Health Research Institute
RECRUITINGColumbia, Maryland, 21044, United States
Contact
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Michigan Orthopedic Surgeons
RECRUITINGBloomfield Hills, Michigan, 48033, United States
Contact
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Pinehurst Surgical Clinic
RECRUITINGPinehurst, North Carolina, 28374, United States
Contact
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Email: •••••@•••••