New nerve block could replace needle in the back for spinal headaches

NCT ID NCT07354464

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a nerve block (sphenopalatine ganglion block) against the standard blood patch for treating severe headaches that can happen after a spinal tap or epidural. The nerve block is less invasive and involves numbing the nose. The trial will enroll 80 adults and measure pain relief over a week.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
lidocaine (nerve block)
What this could lead to
If it works, this could offer a simpler, less invasive treatment for severe headaches after spinal procedures, reducing the need for the more invasive blood patch.
What could go wrong
This is a relatively small Phase 3 trial (80 people). The nerve block may not be as effective as the blood patch, or its pain relief may not last as long.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracranial hypotension Post-Dural Puncture Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Clermont-Ferrand

    RECRUITING

    Clermont-Ferrand, France

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