New drug shows promise for tough Crohn's complication

NCT ID NCT03752970

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 26 times

Summary

This study tested a medicine called spesolimab in 27 adults with Crohn's disease who also have fistulas near the anus. The goal was to see if the drug helps close these fistulas better than a placebo. Participants received either the drug or a placebo by IV every 4 weeks for 24 weeks, and doctors checked their fistulas regularly.

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Contacts and locations

Locations

  • AKH - Medical University of Vienna

    Vienna, 1090, Austria

  • Amsterdam UMC, Locatie AMC

    Amsterdam, 1105 AZ, Netherlands

  • Centre Hospitalier Universitaire de Liège

    Liège, 4000, Belgium

  • Herlev and Gentofte Hospital

    Herlev, 2730, Denmark

  • Hospital Universitari de Girona Doctor Josep Trueta

    Girona, 17007, Spain

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Semmelweis University

    Budapest, 1088, Hungary

  • UZ Leuven

    Leuven, 3000, Belgium

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

Conditions

Explore the condition pages connected to this study.