Can a standardized Watch-and-Wait plan reduce prostate cancer overtreatment?
NCT ID NCT02914873
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a standardized active surveillance protocol to usual care for men with low-risk prostate cancer. The goal is to see if a clear set of rules for when to start treatment can reduce unnecessary treatments and side effects without raising the risk of cancer spread. About 2008 men will take part across multiple centers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
active surveillance (monitoring with delayed treatment if needed)
What this could lead to
If successful, this could help many men with low-risk prostate cancer avoid unnecessary treatments and side effects while staying safe.
What could go wrong
This is a large but early-stage comparison study; the standardized protocol may not prove better than current practice, and some men might still face disease progression.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Akademiska University Hospital
Uppsala, Sweden
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Bedford Hospital
Bedford, United Kingdom
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Croydon University Hospital
Croydon, United Kingdom
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Epsom and St Helier Hospital
London, United Kingdom
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Guy's Hospital
London, United Kingdom
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Helsinki University Hospital
Helsinki, Finland
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Hospital of Vestfold
Tønsberg, Norway
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Linköping University Hospital
Linköping, Sweden
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Odense University Hospital
Odense, Denmark
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Oslo University Hospital
Oslo, Norway
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Queen Elisabeth Hospital
London, United Kingdom
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Rigshospitalet
Copenhagen, Denmark
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Royal Marsden Hospital
London, United Kingdom
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Sahlgrenska University Hospital
Gothenburg, Sweden
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Seinäjoki Central Hospital
Tampere, Finland
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St Olavs University Hospital
Trondheim, Norway
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Sunderby Regional Hospital
Luleå, Sweden
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Sundsvall Regional Hospital
Sundsvall, Sweden
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Umeå University Hospital
Umeå, Sweden
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University Hospital of North Norway
Tromsø, Norway
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Växjö Hospital
Vaxjo, Sweden
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Ålesund Regional Hospital
Ålesund, Norway
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Örebro University Hospital
Örebro, Sweden