New depression drug shows promise in Mid-Stage trial
NCT ID NCT06254612
First seen Nov 03, 2025 · Last updated Apr 25, 2026 · Updated 27 times
Summary
This study tests whether a new medicine called SP-624 can safely reduce depression symptoms in adults with moderate to severe major depressive disorder. About 456 people will receive either SP-624 or a placebo (a dummy pill) for several weeks, and researchers will track changes in depression scores. The goal is to see if SP-624 works better than placebo at easing depression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Accel Clinical
COMPLETEDLakeland, Florida, 33803, United States
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Accelerated Enrollment Solutions
RECRUITINGAtlanta, Georgia, 30328, United States
Contact Phone: •••-•••-••••
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Alivation Research
COMPLETEDLincoln, Nebraska, 68526, United States
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Boston Clinical Trials
RECRUITINGBoston, Massachusetts, 02131, United States
Contact Phone: •••-•••-••••
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CenExel HRI
ACTIVE_NOT_RECRUITINGMarlton, New Jersey, 08053, United States
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Center for Emotional Fitness
RECRUITINGCherry Hill, New Jersey, 08002, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CiTrials
RECRUITINGRiverside, California, 92506, United States
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Clinical Innovations
RECRUITINGBellflower, California, 90706, United States
Contact Phone: •••-•••-••••
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Clinical Neuroscience Solutions
RECRUITINGJacksonville, Florida, 32256, United States
Contact Phone: •••-•••-••••
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Clinical Neuroscience Solutions
RECRUITINGOrlando, Florida, 32801, United States
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Clinical Neuroscience Solutions
RECRUITINGMemphis, Tennessee, 38119, United States
Contact Phone: •••-•••-••••
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Coastal Carolina Research Center
COMPLETEDNorth Charleston, South Carolina, 29405, United States
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Collaborative Neuroscience Research
RECRUITINGTorrance, California, 90504, United States
Contact Phone: •••-•••-••••
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Core Clinical Research
RECRUITINGEverett, Washington, 98201, United States
Contact Phone: •••-•••-••••
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DMI Research
RECRUITINGPinellas Park, Florida, 33782, United States
Contact Phone: •••-•••-••••
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Donald J. Garcia, Jr, MD, PA
RECRUITINGAustin, Texas, 78737, United States
Contact Phone: •••-•••-••••
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Excell Research
RECRUITINGOceanside, California, 92056, United States
Contact Phone: •••-•••-••••
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Future Search Trials of Dallas
COMPLETEDDallas, Texas, 75231, United States
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Grayline Research Center
RECRUITINGWichita Falls, Texas, 76309, United States
Contact Phone: •••-•••-••••
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Haracec Clinical Research
RECRUITINGEl Paso, Texas, 79902, United States
Contact Email: •••••@•••••
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IMA Clinical Research
RECRUITINGPhoenix, Arizona, 85012, United States
Contact Phone: •••-•••-••••
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IMA Clinical Research
RECRUITINGLas Vegas, Nevada, 89102, United States
Contact Phone: •••-•••-••••
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IMA Clinical Research
COMPLETEDAlbuquerque, New Mexico, 87109, United States
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Integrative Clinical Trials
RECRUITINGBrooklyn, New York, 11229, United States
Contact Phone: •••-•••-••••
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MCB Clinical Research Centers
RECRUITINGColorado Springs, Colorado, 80910, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Magnolia Clinical Research
RECRUITINGCary, North Carolina, 27511, United States
Contact Phone: •••-•••-••••
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Midwest Clinical Research Center
COMPLETEDDayton, Ohio, 45417, United States
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Midwest Research Group
RECRUITINGSaint Charles, Missouri, 63304, United States
Contact Phone: •••-•••-••••
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Neurobehavioral Medicine Group
RECRUITINGBloomfield Hills, Michigan, 48302, United States
Contact Phone: •••-•••-••••
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New Hope Clinical Research
RECRUITINGCharlotte, North Carolina, 28211, United States
Contact Phone: •••-•••-••••
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Next Level Clinical Trials
RECRUITINGWest Covina, California, 91790, United States
Contact Phone: •••-•••-••••
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Noble Clinical Research
RECRUITINGTucson, Arizona, 85704, United States
Contact Phone: •••-•••-••••
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North Star Medical Research
RECRUITINGMiddleburg Heights, Ohio, 44130, United States
Contact Phone: •••-•••-••••
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Northwest Clinical Research Center
RECRUITINGBellevue, Washington, 98007, United States
Contact Phone: •••-•••-••••
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Pillar Clinical Research
COMPLETEDRichardson, Texas, 75080, United States
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Pioneer Clinical Research
RECRUITINGNew York, New York, 10016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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R and H Clinical Research
RECRUITINGStafford, Texas, 77477, United States
Contact Phone: •••-•••-••••
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Redbird Research
RECRUITINGLas Vegas, Nevada, 89119, United States
Contact Phone: •••-•••-••••
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Revive Research Institute
RECRUITINGElgin, Illinois, 60123, United States
Contact Phone: •••-•••-••••
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SanRo Clinical Research Group
RECRUITINGBryant, Arkansas, 72022, United States
Contact Phone: •••-•••-••••
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Segal Trials
RECRUITINGLauderhill, Florida, 33319, United States
Contact Phone: •••-•••-••••
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Segal Trials - Miami Lakes
COMPLETEDMiami Lakes, Florida, 33016, United States
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Summit Headlands
RECRUITINGPortland, Oregon, 97210, United States
Contact Phone: •••-•••-••••
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Sun Valley Research Center
RECRUITINGImperial, California, 92251, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunwise Clinical Research
RECRUITINGWalnut Creek, California, 94596, United States
Contact Phone: •••-•••-••••
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Synergy San Diego
RECRUITINGLemon Grove, California, 91945, United States
Contact Phone: •••-•••-••••
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Tandem Clinical Research
RECRUITINGMarrero, Louisiana, 70072, United States
Contact Phone: •••-•••-••••
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UNC Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact Email: •••••@•••••
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Velocity Clinical Research
COMPLETEDMeridian, Idaho, 83642, United States
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Velocity Clinical Research
COMPLETEDBeachwood, Ohio, 44122, United States
Conditions
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