Sound waves and a special drug team up to fight deadly brain tumors

NCT ID NCT07076472

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 32 times

Summary

This early-stage trial tests a new treatment called sonodynamic therapy for people with glioblastoma that has come back or is getting worse. The treatment combines a drug (5-ALA) that makes tumor cells sensitive to sound waves, with focused ultrasound waves that target and destroy those cells. The study aims to find the safest dose and see if this approach can help control the cancer. About 8 adults whose tumors cannot be surgically removed will participate.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.