Can baking soda save kidneys? new trial tests cheap treatment for ICU patients

NCT ID NCT07464431

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving sodium bicarbonate (baking soda) intravenously can reduce major kidney problems or death in critically ill patients with metabolic acidosis and acute kidney injury. About 660 adults in intensive care will receive either sodium bicarbonate or a standard balanced fluid. The main goal is to see if fewer patients die, need dialysis, or have lasting kidney damage within 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sodium bicarbonate

What this could lead to

If it works, this could provide a simple, low-cost treatment to reduce the risk of kidney failure or death in critically ill patients with acute kidney injury.

What could go wrong

This is a phase 4 trial, but previous evidence is limited to a subgroup analysis. The treatment may not show benefit, and sodium bicarbonate can cause side effects like fluid overload or electrolyte imbalances.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acidosis acute kidney injury Critical Illness metabolic acidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••