Can a Two-Drug combo outsmart pancreatic cancer?
NCT ID NCT07756281
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This early-stage trial tests an experimental oral drug called SNV1521, a PARP inhibitor, combined with the RAS-targeting medicine daraxonrasib in adults with pancreatic cancer that cannot be surgically removed or has spread. The main goals are to find safe and tolerable doses of the combination and to look for early signs that it may help control the cancer. Participants receive the drugs in repeating cycles and undergo regular blood tests, scans, and exams to monitor side effects and tumor response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SNV1521 (an oral PARP inhibitor) combined with daraxonrasib (an oral RAS inhibitor)
- What this could lead to
- If this combination proves safe and shows activity, it could lead to a new treatment option for advanced pancreatic cancer, a disease with few effective therapies.
- What could go wrong
- This is an early-phase, small trial focused on safety and dosing, so it may not show clear benefit. The drug combination could cause side effects or fail to control the cancer.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PANCREATIC ACINAR CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a vaccine help fight Hard-to-Treat cancers?
- Blood and gut clues may flag pancreatic cancer risk early
- A high-tech camera may take the guesswork out of spotting a dangerous surgery complication
- MRI might reveal hidden pancreatic risks in obesity
- Can a new PET tracer light up hidden cancers?
- Can a pill rouse the immune system against pancreatic cancer?