Can a phone app help smokers with HIV kick the habit?

NCT ID NCT04949464

Recruiting now Disease control Sponsor: AIDS Malignancy Consortium Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a smartphone app designed for people with HIV can help them quit smoking when combined with a lung cancer screening CT scan. About 100 participants will use the app and get a low-dose CT scan. The goal is to see if this approach is practical and helps people stop smoking.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Positively Smoke Free - Mobile (smartphone app) and low-dose CT scan
What this could lead to: If successful, this could show that combining a tailored smoking cessation app with lung cancer screening helps people with HIV quit smoking, potentially reducing their risk of lung cancer.
What could go wrong: This is a small feasibility study (100 participants) with no control group, so results may not be generalizable. Adherence to the app may be low, and quitting smoking is difficult even with support.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTION TOBACCO-RELATED CARCINOMA

Contacts and locations

Locations

George Washington University
RECRUITING

Washington D.C., District of Columbia, 20052, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10461, United States
Mount Sinai Hospital
RECRUITING

New York, New York, 10029, United States
The Ohio State University James Cancer Hospital
RECRUITING

Columbus, Ohio, 43221, United States
Thomas Jefferson University
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
University of Texas M.D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Virginia Mason Medical Center
RECRUITING

Seattle, Washington, 98101, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Weill Cornell Medicine - Cornell Clinical Trials Unit
RECRUITING

New York, New York, 10010, United States

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