Can a phone app lift depression? new trial puts digital therapy to the test

NCT ID NCT05554289

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested a smartphone app called WL-iCBT that delivers cognitive behavioral therapy through videos, exercises, and interactive tools. 315 adults with mild-to-moderate depression used either the active app or a placebo version for 8 weeks. Researchers measured changes in depression severity, anxiety, and daily functioning to see if the app helps ease symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

smartphone app delivering cognitive behavioral therapy and attention bias modification

What this could lead to

If it works, this could provide a convenient, accessible treatment option for mild-to-moderate depression that people can use at home.

What could go wrong

This is a completed trial, but results are not yet published. The app may not outperform a placebo, and benefits may vary by individual. Digital therapies also require user engagement to be effective.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chengdu Fourth People's Hospital (Chengdu Mental Health Center)

    Chengdu, Sichuan, China

  • Ningbo Kangning Hospital

    Ningbo, Zhejiang, China

  • Quzhou Third Hospital

    Quzhou, Zhejiang, China

  • Shenzhen Kangning Hospital

    Shenzhen, Guangdong, China

  • The Fifth Affiliated Hospital of Sun Yat-sen University

    Zhuhai, Guangdong, China

  • The First Affiliated Hospital of Kunming Medical University

    Kunming, Yunan, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shannxi, China

  • The First Hospital of Hebei Medical University

    Shijiazhuang, Hebei, China

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan, China

  • Zhejiang Provincial Tongde Hospital

    Hangzhou, Zhejiang, China

  • Zhumadian Second People's Hospital

    Zhumadian, Henan, China