Double breathing trouble: study tests two therapies to protect hearts

NCT ID NCT05237505

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how having both sleep apnea and COPD (called overlap syndrome) affects the heart. Researchers will compare people with one or both conditions and test two breathing treatments—a special mask that helps breathing at night and extra oxygen—to see which may improve heart health. The goal is to understand why people with both conditions are at higher risk for heart problems and find better ways to help them.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bi-level positive pressure non invasive ventilation (BIPAP) and nocturnal oxygen therapy

What this could lead to

If successful, this study could point toward better heart treatments for people with both sleep apnea and COPD.

What could go wrong

This is an early phase 2 pilot study with only 240 participants, so results may not apply to everyone. The treatments may not show clear heart benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease mixed connective tissue disease obstructive sleep apnea syndrome overlapping connective tissue disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UCSD Sleep Research

    RECRUITING

    La Jolla, California, 92037, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••