New pill aims to tame Huntington's disease by targeting toxic proteins
NCT ID NCT06873334
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an oral drug called SKY-0515 in 120 adults with Huntington's disease. The goal is to see if it can lower harmful proteins in the blood, slow brain changes, and improve symptoms. Participants must be 25 or older with a confirmed genetic diagnosis and a certain level of independence.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Auckland City Hospital
Auckland, 1023, New Zealand
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Calvary Health Care Bethlehem
Caulfield South, Victoria, 3162, Australia
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Christchurch Neurology Trials Limited
Christchurch, 8011, New Zealand
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Flinders Medical Centre
Adelaide, South Australia, 5042, Australia
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Huntington's Disease Association
Auckland, 0604, New Zealand
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John Hunter Hospital
New Lambton Heights, New South Wales, 2305, Australia
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Launceston General Hospital
Launceston, Tasmania, 7250, Australia
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The Perron Institute for Neurology and Translational Science (Perron Institute)
Nedlands, Western Australia, 6009, Australia
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The Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
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The University of Queensland
Herston, Queensland, 4006, Australia
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Wellington Hospital
Wellington, 6021, New Zealand
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Westmead Hospital
Westmead, New South Wales, 2145, Australia