New pill aims to tackle Huntington's at its source

NCT ID NCT06873334

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests an oral drug called SKY-0515 in 120 adults with Huntington's disease. The goal is to see if it can lower a harmful protein linked to the disease and improve symptoms. Participants take the drug or a placebo for a set period, and researchers monitor changes in protein levels, brain scans, and movement scores.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Auckland City Hospital

    Auckland, 1023, New Zealand

  • Calvary Health Care Bethlehem

    Caulfield South, Victoria, 3162, Australia

  • Christchurch Neurology Trials Limited

    Christchurch, 8011, New Zealand

  • Flinders Medical Centre

    Adelaide, South Australia, 5042, Australia

  • Huntington's Disease Association

    Auckland, 0604, New Zealand

  • John Hunter Hospital

    New Lambton Heights, New South Wales, 2305, Australia

  • Launceston General Hospital

    Launceston, Tasmania, 7250, Australia

  • The Perron Institute for Neurology and Translational Science (Perron Institute)

    Nedlands, Western Australia, 6009, Australia

  • The Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • The University of Queensland

    Herston, Queensland, 4006, Australia

  • Wellington Hospital

    Wellington, 6021, New Zealand

  • Westmead Hospital

    Westmead, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.