Can a genetic 'Patch' fix Huntington's disease? lab test aims to find out

NCT ID NCT06444217

Completed Knowledge-focused Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This study tests a gene therapy technique in the lab using skin cells from people with Huntington's disease. The goal is to see if the therapy can correct the genetic mistake that causes the disease. If it works in these cells, it could be a step toward a future treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RNA trans-splicing gene therapy (tested in the lab on patient-derived skin cells)
What this could lead to: If this lab test succeeds, it could pave the way for a gene therapy that corrects the genetic error causing Huntington's disease.
What could go wrong: This is a very early lab study on cells, not people. The approach may not work in the lab or may not translate to a safe or effective treatment for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HUNTINGTON DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Huntington disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HUNTINGTON DISEASE

Contacts and locations

Locations

ABRIAL

Angers, Maine et Loire, 49933, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.