Heart surgery blood filter shows kidney protection promise in new analysis
NCT ID NCT06781294
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study re-analyzes data from a previous trial of 343 heart surgery patients who received a blood purification device (oXiris) connected to the heart-lung machine. The original trial found a 12% reduction in acute kidney injury within 7 days. Now researchers will examine how the filter affects antibiotics, heparin, and other drugs, and whether certain patient groups benefit more. The goal is to better understand the device's safety and effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Extracorporeal cytokine hemadsorption device (oXiris)
- What this could lead to
- If successful, this analysis could clarify how best to use blood purification during heart surgery to protect kidneys and guide safe antibiotic dosing.
- What could go wrong
- This is a post-hoc analysis of an already completed trial, not a new experiment. Findings may be less reliable and need confirmation in future studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Universitat de Barcelona
L'Hospitalet de Llobregat, Barcelona, 08907, Spain
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Other studies related to the condition(s) this trial covers.
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- Can a common blood thinner be safe for ICU patients with liver issues?
- A urine test that could foresee kidney danger in the ICU