New hope for stomach cancer patients with abdominal spread: experimental drug combo enters trial

NCT ID NCT07384234

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether adding an experimental immunotherapy drug called SHR-1701 to standard chemotherapy can help people with stomach cancer that has spread to the lining of the abdomen. The study will enroll 60 adults and compare two different chemotherapy combinations, with or without SHR-1701. The main goal is to see if the treatment improves survival over two years and whether it can make the cancer removable by surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SHR-1701 (an experimental immunotherapy drug) combined with chemotherapy drugs (paclitaxel, S-1, capecitabine, oxaliplatin)

What this could lead to

If successful, this could offer a new treatment option for people with stomach cancer that has spread to the abdomen, potentially improving survival and making surgery possible.

What could go wrong

This is an early phase 2 trial with only 60 participants, so results are preliminary. The combination may cause significant side effects, and the experimental drug SHR-1701 may not improve outcomes over standard chemotherapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Changhai Hospital

    Shanghai, Shanghai Municipality, China

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact