Heart drug may speed ventilator weaning in ICU

NCT ID NCT07105202

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether levosimendan, a drug that strengthens heart and breathing muscles, can help critically ill patients get off a ventilator faster. About 250 adults who have been on a breathing machine for over 48 hours and failed a breathing test will receive either the drug or a placebo. The goal is to see if the drug increases the number of days alive and free from a ventilator.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Canisius Wilhelmina Ziekenhuis

    RECRUITING

    Nijmegen, Gelderland, 6532SZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Catharina Ziekenhuis Stichting

    NOT_YET_RECRUITING

    Eindhoven, North Brabant, 5623EJ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

    NOT_YET_RECRUITING

    Rotterdam, South Holland, 3015GD, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Intensive Care Medicine, Radboud University

    RECRUITING

    Nijmegen, Gelderland, 6500 HB, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Jeroen Bosch Ziekenhuis Stichting

    RECRUITING

    's-Hertogenbosch, North Brabant, 5223GZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maasstad Ziekenhuis Stichting

    RECRUITING

    Rotterdam, South Holland, 3079DZ, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rijnstate Ziekenhuis Stichting

    RECRUITING

    Arnhem, Gelderland, 6815AD, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sint Franciscus Vlietland Groep Stichting

    RECRUITING

    Rotterdam, South Holland, 3045 PM, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••