Heart drug may speed ventilator weaning in ICU

NCT ID NCT07105202

Recruiting now Disease control Sponsor: Radboud University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether levosimendan, a drug that strengthens heart and breathing muscles, can help critically ill patients get off a ventilator faster. About 250 adults who have been on a breathing machine for over 48 hours and failed a breathing test will receive either the drug or a placebo. The goal is to see if the drug increases the number of days alive and free from a ventilator.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION WEANING FAILURE

Contacts and locations

Locations

Canisius Wilhelmina Ziekenhuis
RECRUITING

Nijmegen, Gelderland, 6532SZ, Netherlands
Catharina Ziekenhuis Stichting
NOT_YET_RECRUITING

Eindhoven, North Brabant, 5623EJ, Netherlands
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
NOT_YET_RECRUITING

Rotterdam, South Holland, 3015GD, Netherlands
Intensive Care Medicine, Radboud University
RECRUITING

Nijmegen, Gelderland, 6500 HB, Netherlands
Jeroen Bosch Ziekenhuis Stichting
RECRUITING

's-Hertogenbosch, North Brabant, 5223GZ, Netherlands
Maasstad Ziekenhuis Stichting
RECRUITING

Rotterdam, South Holland, 3079DZ, Netherlands
Rijnstate Ziekenhuis Stichting
RECRUITING

Arnhem, Gelderland, 6815AD, Netherlands
Sint Franciscus Vlietland Groep Stichting
RECRUITING

Rotterdam, South Holland, 3045 PM, Netherlands

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