Could fewer radiation sessions mean fewer complications for sarcoma patients?
NCT ID NCT03819985
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing a shorter, higher-dose radiation schedule given before surgery for soft tissue sarcoma of the arms, legs, or trunk. The goal is to see if this approach reduces wound complications after surgery while still controlling the cancer. About 122 patients are taking part, and researchers are comparing results to historical data.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hypofractionated radiation therapy
What this could lead to
If successful, this could offer a more convenient and safer pre-surgery radiation option for soft tissue sarcoma patients, with fewer wound complications.
What could go wrong
This is a mid-stage trial with only 122 participants, so results may not apply to all patients. The shorter radiation course might still cause wound problems or not control the cancer as well as standard treatment.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States