Could fewer radiation sessions mean fewer complications for sarcoma patients?

NCT ID NCT03819985

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a shorter, higher-dose radiation schedule given before surgery for soft tissue sarcoma of the arms, legs, or trunk. The goal is to see if this approach reduces wound complications after surgery while still controlling the cancer. About 122 patients are taking part, and researchers are comparing results to historical data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Hypofractionated radiation therapy
What this could lead to
If successful, this could offer a more convenient and safer pre-surgery radiation option for soft tissue sarcoma patients, with fewer wound complications.
What could go wrong
This is a mid-stage trial with only 122 participants, so results may not apply to all patients. The shorter radiation course might still cause wound problems or not control the cancer as well as standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.