Could a quicker gout infusion be just as safe and effective?

NCT ID NCT04511702

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study looked at whether giving the gout medication pegloticase over a shorter time is safe and works well for people with uncontrolled gout who are also taking methotrexate. About 191 adults took part. The main goal was to check for infusion reactions, and a key measure was whether uric acid levels stayed low for at least 80% of month 6.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abigail Rebecca Neiman, MD, PA

    Houston, Texas, 77024, United States

  • Altoona Center for Clinical Research

    Duncansville, Pennsylvania, 16635, United States

  • Amicis Research Center

    Northridge, California, 91324, United States

  • Arizona Arthritis & Rheumatology Research

    Gilbert, Arizona, 85297, United States

  • Arizona Arthritis & Rheumatology Research

    Phoenix, Arizona, 85037, United States

  • Arthritis & Rheumatology Research

    Mesa, Arizona, 85210, United States

  • Arthritis Northwest

    Spokane, Washington, 99204, United States

  • Bradenton Research Center

    Bradenton, Florida, 34205, United States

  • Cape Fear Arthritis Care

    Leland, North Carolina, 28451, United States

  • Chattanooga Research & Medicine PLLC (CHARM)

    Chattanooga, Tennessee, 37404, United States

  • ClinPro Research Solutions

    Tampa, Florida, 33609, United States

  • D&H National Research Centers

    Miami, Florida, 33155, United States

  • D&H Tamarac Research Centers

    Tamarac, Florida, 33321, United States

  • Denver Arthritis Clinic

    Denver, Colorado, 80230, United States

  • ForCare Clinical Research

    Tampa, Florida, 33613, United States

  • GCP Clinical Research

    Tampa, Florida, 33064, United States

  • IRIS Research and Development, LLC

    Plantation, Florida, 33324, United States

  • LIFE Clinical Trials

    Margate, Florida, 33063, United States

  • Long Island Arthritis & Osteoporosis Care

    Babylon, New York, 11702, United States

  • MD Medical Research

    Oxon Hill, Maryland, 20745, United States

  • MedPharmics, LLC

    Metairie, Louisiana, 70006, United States

  • Medvin Clinical Research

    Covina, California, 91722, United States

  • Medvin Clinical Research

    Thousand Oaks, California, 91360, United States

  • Medvin Clinical Research

    Tujunga, California, 91042, United States

  • Napa Research Center

    Pompano Beach, Florida, 33064, United States

  • Orthopedic Physicians Alaska

    Anchorage, Alaska, 99508, United States

  • PMG Research of Hickory, LLC

    Hickory, North Carolina, 28602, United States

  • PMG Research of Salisbury, LLC

    Salisbury, North Carolina, 28144, United States

  • Pioneer Research Solutions Inc - Houston

    Houston, Texas, 77099, United States

  • Prohealth Research Center

    Doral, Florida, 33166, United States

  • Providence Saint John's Health Center

    Santa Monica, California, 90404, United States

  • Research Carolina Elite

    Denver, North Carolina, 28037, United States

  • Santa Fe Rheumatology

    Santa Fe, New Mexico, 87505, United States

  • Shelby Clinical Research, LLC

    Shelby, North Carolina, 28150, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Colorado Division of Rheumatology

    Aurora, Colorado, 80045, United States

  • Velocity Clinical Research Cincinnati

    Cincinnati, Ohio, 45242, United States

  • Velocity Clinical Research, Salt Lake City

    West Jordan, Utah, 84088, United States

  • Western Washington Medical Group

    Bothell, Washington, 98021, United States

Conditions

Explore the condition pages connected to this study.