Could one antibiotic dose before tooth pulling prevent infections in Immune-Weakened patients?
NCT ID NCT07275580
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single dose of amoxicillin before a simple tooth extraction can prevent infections in people with autoimmune rheumatic diseases who are on immune-suppressing medications. Researchers will compare infection rates between those who get the antibiotic and those who get a placebo. The goal is to see if this common practice is actually effective and safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Amoxicillin
What this could lead to
If successful, this could show that a single antibiotic dose is enough to prevent infections after tooth extraction in immunosuppressed patients, reducing unnecessary antibiotic use.
What could go wrong
This is a Phase 4 trial, but it is not yet recruiting and has a moderate size (352 participants). The results may not apply to all autoimmune diseases or extraction types, and the placebo group could show similar infection rates.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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