Shockwave therapy could crack tough heart blockages

NCT ID NCT06662500

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study tests a new device that uses sound waves to break up calcium deposits in heart arteries before placing a stent. About 408 adults with coronary artery disease will receive this treatment. The goal is to see if the device is safe and effective at clearing blockages to improve blood flow.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Basildon University Hospital

    RECRUITING

    Basildon, UK, SS16 5NL, United Kingdom

  • Baylor Scott & White Research Institute Dallas

    RECRUITING

    Dallas, Texas, 75226, United States

  • Baylor Scott and White - The Heart Hospital Baylor Plano

    RECRUITING

    Plano, Texas, 75093, United States

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Bristol Heart Institute

    RECRUITING

    Bristol, UK, BS2 8ED, United Kingdom

  • Centennial Heart

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Columbia University Medical Center/New York Presbyterian Hospital

    RECRUITING

    New York, New York, 10032, United States

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Glenfield Hospital

    RECRUITING

    Leicester, UK, LE3 9QP, United Kingdom

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06112, United States

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

  • Intermountain Medical Center Heart Institute

    RECRUITING

    Salt Lake City, Utah, 84111, United States

  • Leeds Teaching Hospital NHS Trust

    RECRUITING

    Leeds, UK, LS1 3EX, United Kingdom

  • Lenox Hill Hospital

    RECRUITING

    New York, New York, 10075, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Medstar Washington Hospital Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

  • Minneapolis Heart Institute

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

  • NC Heart and Vascular Research, LLC

    RECRUITING

    Raleigh, North Carolina, 27607, United States

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • Overlake Medical Center

    RECRUITING

    Bellevue, Washington, 98004, United States

  • Piedmont Heart Institute

    RECRUITING

    Atlanta, Georgia, 30309, United States

  • Providence St. Vincent

    RECRUITING

    Portland, Oregon, 97225, United States

  • Scripps Health

    RECRUITING

    La Jolla, California, 92037, United States

  • South Denver Cardiology Associates, P.C

    RECRUITING

    Littleton, Colorado, 80120, United States

  • St. Francis Hospital & Heart Center

    RECRUITING

    Roslyn, New York, 11576, United States

  • St. George's Hospital

    RECRUITING

    London, UK, SW17 0RE, United Kingdom

  • St. Thomas Hospital

    RECRUITING

    London, UK, SE1 7EH, United Kingdom

  • Swedish Medical

    RECRUITING

    Seattle, Washington, 98122, United States

  • The Cardiac and Vascular Institute

    RECRUITING

    Gainesville, Florida, 32605, United States

  • The Christ Hospital

    RECRUITING

    Cincinnati, Ohio, 45219, United States

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

  • University of Washington Medical Center

    RECRUITING

    Seattle, Washington, 98195, United States

  • Wellspan York Hospital

    RECRUITING

    York, Pennsylvania, 17403, United States

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