Shockwave therapy could crack tough heart blockages
NCT ID NCT06662500
First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times
Summary
This study tests a new device that uses sound waves to break up calcium deposits in heart arteries before placing a stent. About 408 adults with coronary artery disease will receive this treatment. The goal is to see if the device is safe and effective at clearing blockages to improve blood flow.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Basildon University Hospital
RECRUITINGBasildon, UK, SS16 5NL, United Kingdom
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Baylor Scott & White Research Institute Dallas
RECRUITINGDallas, Texas, 75226, United States
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Baylor Scott and White - The Heart Hospital Baylor Plano
RECRUITINGPlano, Texas, 75093, United States
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Bristol Heart Institute
RECRUITINGBristol, UK, BS2 8ED, United Kingdom
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Centennial Heart
RECRUITINGNashville, Tennessee, 37203, United States
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Columbia University Medical Center/New York Presbyterian Hospital
RECRUITINGNew York, New York, 10032, United States
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
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Glenfield Hospital
RECRUITINGLeicester, UK, LE3 9QP, United Kingdom
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Hartford Hospital
RECRUITINGHartford, Connecticut, 06112, United States
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
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Intermountain Medical Center Heart Institute
RECRUITINGSalt Lake City, Utah, 84111, United States
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Leeds Teaching Hospital NHS Trust
RECRUITINGLeeds, UK, LS1 3EX, United Kingdom
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Lenox Hill Hospital
RECRUITINGNew York, New York, 10075, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Medstar Washington Hospital Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Minneapolis Heart Institute
RECRUITINGMinneapolis, Minnesota, 55407, United States
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NC Heart and Vascular Research, LLC
RECRUITINGRaleigh, North Carolina, 27607, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Overlake Medical Center
RECRUITINGBellevue, Washington, 98004, United States
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Piedmont Heart Institute
RECRUITINGAtlanta, Georgia, 30309, United States
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Providence St. Vincent
RECRUITINGPortland, Oregon, 97225, United States
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Scripps Health
RECRUITINGLa Jolla, California, 92037, United States
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South Denver Cardiology Associates, P.C
RECRUITINGLittleton, Colorado, 80120, United States
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St. Francis Hospital & Heart Center
RECRUITINGRoslyn, New York, 11576, United States
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St. George's Hospital
RECRUITINGLondon, UK, SW17 0RE, United Kingdom
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St. Thomas Hospital
RECRUITINGLondon, UK, SE1 7EH, United Kingdom
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Swedish Medical
RECRUITINGSeattle, Washington, 98122, United States
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The Cardiac and Vascular Institute
RECRUITINGGainesville, Florida, 32605, United States
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The Christ Hospital
RECRUITINGCincinnati, Ohio, 45219, United States
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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University of Washington Medical Center
RECRUITINGSeattle, Washington, 98195, United States
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Wellspan York Hospital
RECRUITINGYork, Pennsylvania, 17403, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which blood thinner is safer for heart patients? a Head-to-Head test
- Can a new heart pump outperform the standard during High-Risk angioplasty?
- AI reads blood flow to predict if heart stents will work
- Battle of the balloons: super High-Pressure vs shockwaves for Rock-Hard arteries
- Scoring balloon aims to crack tough heart plaques for better stent fit
- New balloon tackles tough heart blockages in major registry