New vaccine aims to stop deadly infant diarrhea

NCT ID NCT06663436

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new Shigella vaccine in 200 healthy African infants to see if it can prevent severe diarrhea. The vaccine was given in two doses, and researchers measured immune responses and safety. The trial is now complete, and results will show whether this approach is promising.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Shigella vaccine (altSonflex1-2-3)
What this could lead to
If successful, this vaccine could help protect infants in Africa from severe diarrhea caused by Shigella bacteria.
What could go wrong
This is a small, early-phase trial. The vaccine may not produce strong enough immunity or could have side effects. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Kericho, 20200, Kenya

More trials for these conditions

Other studies related to the condition(s) this trial covers.