New vaccine aims to stop deadly infant diarrhea

NCT ID NCT06663436

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new Shigella vaccine in 200 healthy African infants to see if it can prevent severe diarrhea. The vaccine was given in two doses, and researchers measured immune responses and safety. The trial is now complete, and results will show whether this approach is promising.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Shigella vaccine (altSonflex1-2-3)

What this could lead to

If successful, this vaccine could help protect infants in Africa from severe diarrhea caused by Shigella bacteria.

What could go wrong

This is a small, early-phase trial. The vaccine may not produce strong enough immunity or could have side effects. Results may not apply to all populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diarrheal disease shigellosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Kericho, 20200, Kenya