Baby teeth stem cells tested as possible ALS treatment

NCT ID NCT06889857

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests a substance made from stem cells from baby teeth (SHED-CM) in 10 people with ALS. The goal is to see if it is safe and if it might slow the disease. Participants receive the treatment intravenously over 12 weeks, with follow-up for 4 more weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SHED-CM (stem cell from human exfoliated deciduous teeth conditioned media)

What this could lead to

If it works, this could point toward a way to slow ALS progression and improve quality of life.

What could go wrong

This is a very early, small trial with only 10 participants, so results may not apply to everyone. The treatment may not work or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hitonowa Medical

    Chiyoda City, Tokyo, 102-0085, Japan