Hormones and healing: could sex hormones shape Post-Surgery pain in teens?

NCT ID NCT06023225

Recruiting now Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study looks at how sex hormones like testosterone, estrogen, and progesterone relate to pain levels and opioid use after surgery in girls aged 11 to 16. Researchers will also examine whether immune factors help explain these effects. The goal is to better understand why pain and opioid needs vary, which could lead to more tailored pain care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If links are found, this could point toward personalized pain management strategies for adolescent girls after surgery.
What could go wrong: This is an observational study, not a treatment trial. It will identify associations, not prove cause and effect, and results may not apply to other groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPIOID USE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

opioid abuse Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID USE POSTOPERATIVE PAIN

Contacts and locations

Show contact details

Locations

Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.