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Scientists hunt for genetic clues to severe viral infections

NCT ID NCT01011712

Recruiting now Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 09, 2026 · Updated 4 times

Summary

This study looks at people who have had unusually severe or long-lasting viral infections, like serious cases of herpes, HPV, or the flu. Researchers want to find out if these people have hidden immune system or genetic problems that make them more vulnerable. Up to 600 participants and their relatives will provide blood and skin samples for testing. The goal is to better understand why some people struggle to fight off certain viruses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could reveal new genetic or immune targets for future treatments for severe viral infections.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and findings may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adenoviridae infectious disease cytomegalovirus infection Epstein-Barr virus infection herpes simplex infectious disease human papilloma virus infection inborn error of immunity varicella zoster infection viral infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CMV EBV HPV HSV VZV

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.