Gut feeling: probiotic plus antidepressant shows promise for teen depression
NCT ID NCT07539805
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a probiotic (Lactobacillus crispatus) to the antidepressant sertraline helps reduce depression symptoms more than sertraline alone in teens aged 12-18 with major depressive disorder. Sixty participants will take either the probiotic or a placebo for 8 weeks, with regular check-ins to monitor mood and safety. The goal is to see if this combination offers a better way to ease depression in young people.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Affiliated Dazu's Hospital of Chongqing Medical University
NOT_YET_RECRUITINGLonggang, Chongqing Municipality, 404100, China
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The Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, Yuzhong, 400010, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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