Gut feeling: could a probiotic boost depression treatment in teens?

NCT ID NCT07539805

First seen Apr 22, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This study looks at whether adding a probiotic (Lactobacillus crispatus) to the antidepressant sertraline helps teens aged 12-18 with major depression feel better. Sixty participants will receive either the probiotic or a placebo with their medication for 8 weeks. The goal is to see if the combination reduces depressive symptoms more than medication alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE DISORDER (MDD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Affiliated Hospital of Chongqing Medical University

    Chongqing, Yuzhong, 400010, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.