Could a 5-Day brain stimulation blitz ease depression in PTSD?

NCT ID NCT07682207

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This pilot study tests whether a faster schedule of non-invasive magnetic brain stimulation, called accelerated intermittent theta burst stimulation (iTBS), is practical and safe for adults with both PTSD and major depression. Participants receive six short sessions per day for five days. The study focuses on feasibility, tolerability, and changes in symptoms and brain activity over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

accelerated intermittent theta burst stimulation (iTBS)

What this could lead to

If this faster schedule proves practical and safe, it could offer a quicker, non-invasive treatment option for depression in people with PTSD.

What could go wrong

This is a very small, early feasibility study with only 16 participants. It is not designed to prove effectiveness, and results may not apply to everyone. Side effects like headache or discomfort are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE DISORDER (MDD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

combat disorder Depression major depressive disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Joseph's Health Care London, Parkwood Institute Mental Health Care Building

    London, Ontario, N6C 0A7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact