Can a 3-Day drug cocktail rejuvenate kidney patients?
NCT ID NCT02848131
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a short course of two drugs, dasatinib and quercetin, can clear senescent (aging) cells in people with chronic kidney disease. The goal is to see if this reduces frailty and improves stem cell function. Thirty participants aged 40-80 with moderate-to-severe kidney disease will take the drugs for 3 days and be monitored for changes in cell health and physical ability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dasatinib and Quercetin
What this could lead to
If it works, this could point toward a treatment that reduces frailty and improves physical function in people with chronic kidney disease.
What could go wrong
This is a small, early-phase study with only 30 participants, so results may not apply broadly. The drugs are taken for just 3 days, so any benefits may be short-lived or not occur at all.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic Florida
Jacksonville, Florida, 32224, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States