Could a diabetes drug curb opioid cravings? new trial aims to find out

NCT ID NCT06639464

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tests whether semaglutide (a weekly injection used for diabetes and weight loss) can reduce cravings and prevent relapse in people with opioid use disorder who are also taking buprenorphine. About 46 adults will receive either semaglutide or a placebo for 12 weeks. The goal is to see if the drug helps control the urge to use opioids and improves treatment outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPIOID USE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.