Could a diabetes drug lift depression? new trial explores semaglutide's mood effects
NCT ID NCT07136714
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether semaglutide, a drug used for diabetes and weight loss, can help improve mood in people with major depression who are also overweight or obese. Over 26 weeks, 116 participants will receive either semaglutide or a placebo added to their usual depression treatment. The main goal is to see if depressive symptoms decrease more with semaglutide.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mental Health Centre North Zealand
RECRUITINGHillerød, Denmark, 3400, Denmark
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