Could a diabetes drug lift depression? new trial explores semaglutide's mood effects
NCT ID NCT07136714
First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 19 times
Summary
This study tests whether semaglutide, a once-weekly injection used for weight loss and diabetes, can help improve mood in people with major depression who are also overweight or obese. Over 26 weeks, 116 participants will receive either semaglutide or a placebo, in addition to their usual depression treatment. The main goal is to see if depressive symptoms decrease more with semaglutide than with placebo.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mental Health Centre North Zealand
RECRUITINGHillerød, Denmark, 3400, Denmark
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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