Weight-Loss drug may boost heart procedure success in AF patients

NCT ID NCT07389941

First seen Feb 05, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This study tests whether taking semaglutide (a weight-loss drug) before a standard heart procedure called catheter ablation helps people with obesity and atrial fibrillation stay free from abnormal heart rhythms for a year. About 240 adults with a BMI of 30 or higher (or 28 with related health issues) will receive either semaglutide or usual care before their first ablation. The goal is to see if pre-treatment improves long-term heart rhythm control.

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