New hope for kids with brain tumors: targeted drug shows promise

NCT ID NCT01089101

First seen Jan 11, 2026 · Last updated May 06, 2026 · Updated 23 times

Summary

This study tests a drug called selumetinib in children and young adults with a slow-growing brain tumor (low grade glioma) that has come back or not responded to other treatments. The goal is to find the best dose and see how well it shrinks or stabilizes the tumor. About 217 participants will receive the drug to control the disease and manage symptoms.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOW GRADE GLIOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

    Houston, Texas, 77030, United States

  • Children's Healthcare of Atlanta - Arthur M Blank Hospital

    Atlanta, Georgia, 30329, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh, Pennsylvania, 15224, United States

  • Children's Memorial Outpatient Center in Lincoln Park

    Chicago, Illinois, 60614, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Lucile Packard Children's Hospital Stanford University

    Palo Alto, California, 94304, United States

  • Lurie Children's Hospital-Chicago

    Chicago, Illinois, 60611, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • Saint Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • UCSF Medical Center-Mount Zion

    San Francisco, California, 94115, United States

  • UCSF Medical Center-Parnassus

    San Francisco, California, 94143, United States

Conditions

Explore the condition pages connected to this study.