Targeted pill shows promise against hard-to-treat thyroid and other cancers

NCT ID NCT04280081

First seen Apr 25, 2026 ยท Last updated Apr 25, 2026

Summary

This study tests an oral drug called selpercatinib in 77 people in China who have advanced solid tumors or medullary thyroid cancer with a specific RET gene change. The main goal is to see if the drug can shrink tumors and how safe it is. Participants take the drug daily and are monitored for response and side effects.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, 200032, China

  • Hunan Cancer Hospital

    Changsha, Hunan, 410013, China

  • Jilin Cancer Hospital

    Changchun, Jilin, 130000, China

  • Jinan Central Hospital

    Jinan, Shandong, 250013, China

  • Shanghai Chest Hospital

    Shanghai, Shanghai/China, 200030, China

  • Shanghai East Hospital

    Shanghai, Shanghai Municipality, 200120, China

  • Southern Medical University Nanfang Hospital

    Guangzhou, Guangdong, 510515, China

  • The First Affiated Hospital Of Guangzhou Medical University

    Guangzhou, Guangdong, 510120, China

  • The First Affiliated Hospital, Zhejiang University

    Hangzhou, Zhejiang, 310003, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310022, China

  • Zhejiang Provincial People's Hospital

    Hangzhou, Zhejiang, 310014, China

Conditions

Explore the condition pages connected to this study.