New study aims to find the best sedation cocktail for Kids' MRIs

NCT ID NCT07369128

Recruiting now Symptom relief Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares different doses of two sedative drugs, propofol and dexmedetomidine, in children aged 1-12 undergoing MRI scans. The goal is to find the combination that provides adequate sedation with fewer side effects and faster recovery. Researchers will measure drug consumption, emergence delirium, and adverse events.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propofol and Dexmedetomidine
What this could lead to: If successful, this could identify a safer, more efficient sedation method for children undergoing MRI, reducing side effects and recovery time.
What could go wrong: This is a small, early-phase trial (105 participants) focused on dosing, not a definitive test of safety or efficacy. Results may not apply to all children or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEXMEDETOMIDINE EMERGENCE DELIRIUM, ANESTHESIA MRI SEDATION PEDIATRIC SEDATION PROPOFOL DOSAGE RECOVERY TIME

Contacts and locations

Locations

Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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