New hope for DVT patients: Clot-Removing procedures as a backup when blood thinners fail
NCT ID NCT06486181
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times
Summary
This study tests whether using a catheter to deliver clot-dissolving drugs or a device to physically remove the clot can help people with acute deep vein thrombosis (DVT) who do not improve after one week of blood thinners. About 100 adults aged 18 to 75 with acute DVT in the leg will be randomly assigned to either continue standard care or receive one of these procedures. Researchers will compare symptom scores and clot burden to see if the procedures are safe and effective.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEEP VENOUS THROMBOSIS are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
RUSH University Medical Center
Chicago, Illinois, 60612, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
catheter-directed thrombolysis or mechanical thrombectomy
What this could lead to
If it works, this could provide a safe and effective second-line option for people with acute DVT who do not respond to standard blood thinners.
What could go wrong
This is a Phase 4 trial with only 100 participants, so results may not apply to everyone. The procedures carry risks like bleeding or vessel damage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.