Can a chill and a silver solution make dental shots less painful for kids?
NCT ID NCT07326241
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at two simple methods to help local anesthesia work better for children aged 6-12 with a condition called Molar-Incisor Hypomineralization (MIH), which makes teeth sensitive and hard to numb. Researchers will apply either silver diamine fluoride or a cold pack to the gum before giving a standard dental injection, then measure pain during treatment. The goal is to find a way to reduce discomfort and anxiety for these kids during dental procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Silver diamine fluoride (SDF) and intraoral cryotherapy (cold application)
What this could lead to
If it works, this could offer a simple, low-cost way to make dental procedures less painful for children with MIH, improving their experience and cooperation.
What could go wrong
This is a small, early-stage study (75 children) that hasn't started yet. Results may not apply to all cases, and the benefits might be modest or not statistically significant.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mersin University, School of Dentistry
Mersin, Turkey (Türkiye)
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Çanakkale Onsekiz Mart University, School of Dentistry
Çanakkale, Turkey (Türkiye)