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Routine blood test could spot silent liver disease

NCT ID NCT05880173

Completed Diagnosis Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 5 times

Summary

This study is testing whether a common blood test, called FIB4, can help find people with advanced liver fibrosis (serious liver scarring) who don't know they have it. About 500 adults aged 18-70 with a high FIB4 result will get a more detailed liver check, including a special ultrasound and possibly a biopsy. The goal is to see if this screening approach works well enough to become a standard early detection tool.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
FIB4 blood test and FibroScan
What this could lead to
If successful, this could lead to a simple, routine blood test to catch serious liver scarring early in people who don't know they have it.
What could go wrong
This is an early screening study, not a treatment trial. The blood test may produce false positives or miss some cases, and the results need further validation before widespread use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fibrotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED LIVER FIBROSIS SCREENING

Contacts and locations

Locations

  • Centre Hospitalier de Lens

    Lens, France

  • Chu Angers

    Angers, 49000, France

  • Chu Bordeaux

    Angers, 49000, France

  • Chu Grenoble Alpes

    Grenoble, France

  • Chu Nancy

    Nancy, France

  • Hopital Saint Joseph

    Marseille, France

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