New hope for schizophrenia: study tests switching to SEP-363856
NCT ID NCT05628103
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how well a new drug, SEP-363856, works and how safe it is for people with schizophrenia who switch from their current antipsychotic medication. About 101 adults with stable schizophrenia took part over 8 weeks. The main goal was to see how many stopped the study due to side effects or lack of benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Advanced Discovery Research LLC
Atlanta, Georgia, 30318, United States
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Advanced Research Center, Inc.
Anaheim, California, 92805, United States
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Atlanta Behavioral Research
Atlanta, Georgia, 30358, United States
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Atlanta Center for Medical Research
Atlanta, Georgia, 30331, United States
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CBH Health
Gaithersburg, Maryland, 20877, United States
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CMB Clinical Trials
Santee, California, 92071, United States
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California Neuropsychopharmacology Clinical Research Institute, LLC (CNRI-San Diego, LLC)
San Diego, California, 92102, United States
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Cenexel CNS Research
Torrance, California, 90502, United States
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Charak Clinical Research Center
Garfield Heights, Ohio, 44125, United States
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Clinical Innovations Inc.
Bellflower, California, 90706, United States
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Clinical Innovations, Inc
Riverside, California, 92506, United States
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Clinical Trials of America, LLC
Hickory, North Carolina, 28601, United States
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Collaborative Neuroscience Research, LLC
Garden Grove, California, 92845, United States
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Hassman Research Institute
Berlin, New Jersey, 08009, United States
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IMA Clinical Research
Las Vegas, Nevada, 89102, United States
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Larkin Behavioral Health Services
Hollywood, Florida, 33021, United States
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New Hope Clinical Research
Charlotte, North Carolina, 28211, United States
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Nova Psychiatry, Inc.
Orlando, Florida, 32803, United States
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Pillar Clinical Research, LLC
Richardson, Texas, 75080, United States
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Premier Clinical Research Institute, Inc.
Miami, Florida, 33122, United States
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ProScience Research Group
Culver City, California, 90230, United States
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PsychCare Consultants Research
St Louis, Missouri, 63128, United States
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Synergy San Diego
Lemon Grove, California, 91945, United States
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Uptown Research
Chicago, Illinois, 60640, United States
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Wellness Research Center
Miami, Florida, 33135, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a new pill for schizophrenia pass its first human test?
- Can a new daily pill offer safer Long-Term control of schizophrenia?
- Can an Anti-Seizure drug quiet the brain and sharpen thinking in schizophrenia?
- Can a dissolving film tame agitation in schizophrenia?
- Can a phone app teach the brain to read social cues?
- Can a gentle brain current silence voices that medication Can't?