New hope for schizophrenia: study tests switching to SEP-363856

NCT ID NCT05628103

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at how well a new drug, SEP-363856, works and how safe it is for people with schizophrenia who switch from their current antipsychotic medication. About 101 adults with stable schizophrenia took part over 8 weeks. The main goal was to see how many stopped the study due to side effects or lack of benefit.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Discovery Research LLC

    Atlanta, Georgia, 30318, United States

  • Advanced Research Center, Inc.

    Anaheim, California, 92805, United States

  • Atlanta Behavioral Research

    Atlanta, Georgia, 30358, United States

  • Atlanta Center for Medical Research

    Atlanta, Georgia, 30331, United States

  • CBH Health

    Gaithersburg, Maryland, 20877, United States

  • CMB Clinical Trials

    Santee, California, 92071, United States

  • California Neuropsychopharmacology Clinical Research Institute, LLC (CNRI-San Diego, LLC)

    San Diego, California, 92102, United States

  • Cenexel CNS Research

    Torrance, California, 90502, United States

  • Charak Clinical Research Center

    Garfield Heights, Ohio, 44125, United States

  • Clinical Innovations Inc.

    Bellflower, California, 90706, United States

  • Clinical Innovations, Inc

    Riverside, California, 92506, United States

  • Clinical Trials of America, LLC

    Hickory, North Carolina, 28601, United States

  • Collaborative Neuroscience Research, LLC

    Garden Grove, California, 92845, United States

  • Hassman Research Institute

    Berlin, New Jersey, 08009, United States

  • IMA Clinical Research

    Las Vegas, Nevada, 89102, United States

  • Larkin Behavioral Health Services

    Hollywood, Florida, 33021, United States

  • New Hope Clinical Research

    Charlotte, North Carolina, 28211, United States

  • Nova Psychiatry, Inc.

    Orlando, Florida, 32803, United States

  • Pillar Clinical Research, LLC

    Richardson, Texas, 75080, United States

  • Premier Clinical Research Institute, Inc.

    Miami, Florida, 33122, United States

  • ProScience Research Group

    Culver City, California, 90230, United States

  • PsychCare Consultants Research

    St Louis, Missouri, 63128, United States

  • Synergy San Diego

    Lemon Grove, California, 91945, United States

  • Uptown Research

    Chicago, Illinois, 60640, United States

  • Wellness Research Center

    Miami, Florida, 33135, United States