Can zapping cancer spots with Super-Precise radiation delay the disease?

NCT ID NCT03808337

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving a very focused, high-dose radiation treatment (SBRT) to all visible cancer spots can delay the cancer from getting worse in people with breast or lung cancer that has spread to 1-5 places. About 145 participants will either receive standard care alone or standard care plus SBRT to each metastasis. The goal is to see if the radiation helps keep the disease under control longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic body radiotherapy (SBRT) – a precise, high-dose radiation treatment

What this could lead to

If it works, this could show that targeting all visible cancer spots with radiation helps keep the disease from getting worse for longer, potentially improving control of metastatic cancer.

What could go wrong

This is a mid-stage trial with only 145 participants, so results may not apply to everyone. SBRT can cause side effects like fatigue or damage to nearby organs, and it may not improve survival or prevent new metastases.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm non-small cell lung carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baptist Alliance - McI

    RECRUITING

    Miami, Florida, 33143, United States

    Contact Phone: •••-•••-••••

  • Hartford Healthcare

    RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact Phone: •••-•••-••••

  • Lehigh Valley Health Network

    RECRUITING

    Allentown, Pennsylvania, 18103, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Basking Ridge

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center @ Commack

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Natera, Inc. (Data and Specimen Analysis Only)

    NOT_YET_RECRUITING

    San Carlos, California, 94070, United States

    Contact Phone: •••-•••-••••

  • WCHN Norwalk Hospital - Data Collection

    RECRUITING

    Norwalk, Connecticut, 06850, United States

    Contact Phone: •••-•••-••••