New radiation boost aims to improve prostate cancer control

NCT ID NCT02016248

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether adding a short, high-dose radiation boost to standard radiation therapy can safely improve treatment for men with unfavorable localized prostate cancer. The boost is delivered non-invasively using stereotactic body radiotherapy (SBRT), similar to a needle-free version of brachytherapy. Researchers will track cancer control, side effects, and quality of life in 150 participants over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic body radiotherapy (SBRT) boost

What this could lead to

If successful, this approach could offer a more effective, non-invasive way to treat unfavorable localized prostate cancer, potentially reducing the chance of cancer returning.

What could go wrong

This is a single-arm study with no comparison group, so it's unclear if the SBRT boost is better than standard treatment. Side effects like urinary or bowel problems are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Long Beach Memorial Medical Center

    RECRUITING

    Long Beach, California, 90806, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orange Coast Memorial Medical Center

    RECRUITING

    Fountain Valley, California, 92708, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saddleback Memorial Medical Center

    RECRUITING

    Laguna Hills, California, 92653, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••