New hope for young sarcoma patients after standard treatments fail

NCT ID NCT02945800

Summary

This study tested whether combining two chemotherapy drugs, nab-paclitaxel and gemcitabine, could help control cancer in teenagers and young adults whose bone or soft tissue sarcoma had returned or stopped responding to standard treatments. The main goals were to see if the combination could shrink or stop tumors from growing and to measure how long patients lived without their cancer getting worse. Researchers also closely monitored side effects to understand the treatment's safety.

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Contacts and locations

Locations

  • A.I. duPont Hospital for Children, Delaware - Nemours

    Wilmington, Delaware, 19603, United States

  • Carolinas Medical Center, Levine Cancer Institute

    Charlotte, North Carolina, 28303, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Connecticut Children's Medical Center

    Hartford, Connecticut, 06103, United States

  • H. Lee Moffitt Cancer Center and Research Institute, Coordinating Center

    Tampa, Florida, 33612, United States

  • Holtz Children's Hospital at the University of Miami

    Miami, Florida, 33136, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Nemours Children's Clinic

    Jacksonville, Florida, 32207, United States

  • Shand's Hospital for Children at the University of Florida

    Gainesville, Florida, 32608, United States

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21231, United States

  • University of Alabama at Birmingham Comprehensive Cancer Center

    Birmingham, Alabama, 35294, United States

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • Vanderbilt - Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.