New drug targets pancreatic cancer before surgery

NCT ID NCT07645651

First seen Jun 17, 2026 · Last updated Jun 19, 2026 · Updated 1 time

Summary

This early-stage trial tests a drug called samuraciclib in 15 people with localized pancreatic cancer that can be surgically removed. Participants will take the drug for about two weeks before their planned surgery. Researchers will check safety and look for changes in tumor cells to see if the drug hits its target. The goal is to gather initial evidence for a possible future treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

samuraciclib (a CDK7 inhibitor drug)

What this could lead to

If successful, this could point toward a new treatment option for localized pancreatic cancer.

What could go wrong

This is a very early Phase 1b trial with only 15 people. It is designed mainly to check safety and biological activity, not to prove the drug works. Many early-stage cancer drugs do not advance to larger trials.

Conditions

The condition(s) this trial relates to.

pancreatic adenocarcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.