Could a gout drug help preterm adults handle salt?
NCT ID NCT04026776
First seen Jun 24, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This study looks at how salt in the diet affects blood pressure in young adults who were born prematurely. Researchers will test whether the drug allopurinol can reduce salt sensitivity. 120 participants will follow high- and low-salt diets, and some will also take allopurinol to see if it helps control blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Allopurinol
What this could lead to
If successful, this could point toward a way to lower blood pressure in people born preterm by reducing salt sensitivity.
What could go wrong
This is a very early, small study (Phase 1, 120 participants). It only looks at short-term effects, and allopurinol may not work for everyone or have lasting benefits.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SALT; EXCESS are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Wake Forest University Health Sciences
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact