Could a common heart drug help dialysis patients?

NCT ID NCT07417215

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether the drug sacubitril/valsartan can improve heart function in people with heart failure who are on chronic hemodialysis. 52 patients were split into two groups: one received the drug, the other standard care. Researchers measured changes in heart ultrasound and blood markers over 2 months to see if the drug helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sacubitril/valsartan

What this could lead to

If it works, this could point toward a new treatment option for heart failure in people on dialysis, a group with few effective therapies.

What could go wrong

This is a small, early-phase study with only 52 participants and a short 2-month follow-up. The drug is not yet approved for dialysis patients, and results may not apply to broader populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Clinical Hospital Mostar

    Mostar, 88000, Bosnia and Herzegovina