New drug combo targets deadly brain tumors in early trial

NCT ID NCT06806228

First seen Nov 18, 2025 · Last updated May 01, 2026 · Updated 17 times

Summary

This early-phase study tests whether adding the experimental drug S-Gboxin to standard radiation and chemotherapy can help control glioblastoma and diffuse midline glioma, two aggressive brain cancers. About 10 participants whose cancer has returned or worsened will receive the combination. The study uses brain scans to measure changes in tumor activity and size, and tracks survival and side effects over 12 months.

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Contacts and locations

Locations

  • Kazakh Institute of Oncology and Radiology

    Almaty, 490 078, Kazakhstan

  • National Cancer Institute

    Kyiv, 33/43, Ukraine

  • Tbilisi Cancer Centre

    Tbilisi, 0198, Georgia

Conditions

Explore the condition pages connected to this study.