New combo therapy aims to tame deadly transplant complication

NCT ID NCT07184853

First seen Sep 30, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tests whether adding etanercept to the standard drug ruxolitinib works better for severe graft-versus-host disease (GVHD) that doesn't respond to steroids. GVHD is a life-threatening complication after a stem cell transplant where donor cells attack the patient's body. About 122 people aged 12-70 will be randomly assigned to get either ruxolitinib alone or ruxolitinib plus etanercept, and researchers will check response at day 28.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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