Can a common plant compound and vitamin c tame fatty liver?

NCT ID NCT07310407

Not yet recruiting Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking rutin (a plant compound found in buckwheat and citrus) along with vitamin C can reduce inflammation and oxidative stress in people with metabolic fatty liver disease (MASLD). 120 adults will take either rutin plus vitamin C, vitamin C alone, or follow a Mediterranean diet and exercise program for 12 weeks. The goal is to see if the combination improves markers of liver injury better than vitamin C or lifestyle changes alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Rutin and Vitamin C
What this could lead to: If it works, this could point toward a simple, low-cost supplement combination to help manage fatty liver disease by reducing inflammation and liver damage.
What could go wrong: This is a small, early-phase trial (120 people) testing only short-term effects on biomarkers, not long-term health outcomes. The results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NAFLD

Contacts and locations

Locations

National Hepatology and Tropical Medicine Research Institute (NHTMRI)

Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.