Allergy drug could tame gut inflammation in colitis

NCT ID NCT07064707

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tests whether rupatadine, an allergy medicine, can help control inflammation in people with mild-to-moderate ulcerative colitis. About 60 adults will take rupatadine or a standard treatment (mesalamine) for several weeks. The goal is to see if rupatadine reduces symptoms like diarrhea and rectal bleeding.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
rupatadine
What this could lead to
If it works, this could point toward a new oral treatment option for mild-to-moderate ulcerative colitis, helping control inflammation and symptoms.
What could go wrong
This is a small, early-phase trial with only 60 people. It may not show enough benefit or could have side effects. Success is far from guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alexandria University

    RECRUITING

    Alexandria, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.