Brain zaps could silence voices that drugs Can't stop

NCT ID NCT01373866

Completed Symptom relief Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a non-invasive brain stimulation technique called rTMS, guided by MRI scans, could reduce severe hallucinations in people with schizophrenia who don't respond to medication. 85 participants received either MRI-guided or standard rTMS over 5 days. The goal was to see if personalized targeting improves symptom relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS)
What this could lead to: If it works, this could offer a non-drug option to ease hallucinations in people with schizophrenia who don't respond to medication.
What could go wrong: This is a small, completed trial with 85 people. Results may not apply to everyone, and the effect might be modest or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hallucinations perceptual disorders schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HALLUCINATIONS PERCEPTUAL DISORDERS SCHIZOPHRENIA

Contacts and locations

Locations

Lille University Hospital Centre

Lille, F-59037, France
Saint-Anne Psychiatric Hospital

Paris, 75005, France

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