Brain zaps before therapy may help kick cocaine habit

NCT ID NCT05974202

First seen Apr 12, 2026 · Last updated Jun 20, 2026 · Updated 10 times

Summary

This study tests whether a non-invasive brain stimulation technique called rTMS, given before cognitive-behavioral therapy, can help adults with cocaine use disorder quit. Thirty participants will receive either real or sham rTMS daily for 3 weeks, followed by 12 weeks of weekly therapy. The goal is to see if the combination is safe, feasible, and leads to abstinence.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • New York State Psychiatric Institute (NYSPI) / Substance Treatment and Research Service (STARS)

    New York, New York, 10019, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive transcranial magnetic stimulation (rTMS)

What this could lead to

If it works, this could point toward a new way to boost therapy for cocaine addiction, helping people stay abstinent.

What could go wrong

This is a very small early-stage trial (30 people) testing feasibility and brain effects, not yet proven to work. The sham group also gets therapy, so the added benefit of rTMS may be small or none.

Conditions

The condition(s) this trial relates to.

Cocaine-Related Disorders follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.