Radioactive beads take aim at untreatable liver tumors

NCT ID NCT05953337

Ongoing Disease control Sponsor: ABK Biomedical Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a treatment called Eye90 microspheres for people with liver cancer that cannot be removed by surgery. The microspheres are tiny glass beads containing radioactive yttrium-90, which are injected into the liver's blood vessels to deliver radiation directly to tumors. The goal is to shrink the tumors and control the cancer. About 120 participants will be enrolled to see how well the treatment works and how safe it is.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Yttrium-90 (Y-90) glass microspheres (Eye90)

What this could lead to

If it works, this could offer a new, effective way to shrink liver tumors and control the disease in patients who cannot have surgery.

What could go wrong

This is an early-stage study with only 120 participants, so results may not apply to everyone. The treatment involves radiation, which can cause side effects like fatigue or liver damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma liver cancer liver disorder Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATOCELLULAR CARCINOMA HEPATOCELLULAR CARCINOMA NON-RESECTABLE LIVER CANCER

Contacts and locations

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Locations

AdventHealth Radiation Oncology at Altamonte Springs

Altamonte Springs, Florida, 32701, United States
Beth Israel Deaconess

Boston, Massachusetts, 02215, United States
Charlotte Radiology

Charlotte, North Carolina, 28202, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Froedtert Hospital/Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
HCA Healthcare Research Institute (Sarah Cannon)

Nashville, Tennessee, 37203, United States
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Inland Imaging

Spokane, Washington, 99203, United States
Miami Cardiac and Vascular Institute at Baptist Hospital Miami

Miami, Florida, 33176, United States
Northwestern University Memorial Hospital

Chicago, Illinois, 60611, United States
Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States
Piedmont Hospital

Atlanta, Georgia, 30309, United States
SSM Health Saint Louis University

St Louis, Missouri, 63104, United States
The University of Arizona Cancer Center

Tucson, Arizona, 85719, United States
University of California - Irvine

Orange, California, 92867, United States
University of Illinois Hospital and Health Sciences System

Chicago, Illinois, 60612, United States
University of Iowa Health Care

Iowa City, Iowa, 52242, United States
University of Louisville

Louisville, Kentucky, 40202, United States
University of Missouri - Ellis Fischel Cancer Center

Columbia, Missouri, 65212, United States
University of Utah

Salt Lake City, Utah, 84112, United States
Vancouver Coastal Health Research Institution (VCHRI)

Vancouver, British Columbia, V5Z 1M9, Canada
Weill Cornell Medicine-New York Presbyterian Hospital

New York, New York, 10065, United States