Radioactive beads take aim at untreatable liver tumors
NCT ID NCT05953337
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a treatment called Eye90 microspheres for people with liver cancer that cannot be removed by surgery. The microspheres are tiny glass beads containing radioactive yttrium-90, which are injected into the liver's blood vessels to deliver radiation directly to tumors. The goal is to shrink the tumors and control the cancer. About 120 participants will be enrolled to see how well the treatment works and how safe it is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Yttrium-90 (Y-90) glass microspheres (Eye90)
- What this could lead to
- If it works, this could offer a new, effective way to shrink liver tumors and control the disease in patients who cannot have surgery.
- What could go wrong
- This is an early-stage study with only 120 participants, so results may not apply to everyone. The treatment involves radiation, which can cause side effects like fatigue or liver damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AdventHealth Radiation Oncology at Altamonte Springs
Altamonte Springs, Florida, 32701, United States
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Beth Israel Deaconess
Boston, Massachusetts, 02215, United States
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Charlotte Radiology
Charlotte, North Carolina, 28202, United States
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Emory University Hospital Midtown
Atlanta, Georgia, 30308, United States
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Froedtert Hospital/Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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HCA Healthcare Research Institute (Sarah Cannon)
Nashville, Tennessee, 37203, United States
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Inland Imaging
Spokane, Washington, 99203, United States
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Miami Cardiac and Vascular Institute at Baptist Hospital Miami
Miami, Florida, 33176, United States
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Northwestern University Memorial Hospital
Chicago, Illinois, 60611, United States
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Ochsner Clinic Foundation
New Orleans, Louisiana, 70121, United States
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Piedmont Hospital
Atlanta, Georgia, 30309, United States
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SSM Health Saint Louis University
St Louis, Missouri, 63104, United States
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The University of Arizona Cancer Center
Tucson, Arizona, 85719, United States
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University of California - Irvine
Orange, California, 92867, United States
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University of Illinois Hospital and Health Sciences System
Chicago, Illinois, 60612, United States
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University of Iowa Health Care
Iowa City, Iowa, 52242, United States
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University of Louisville
Louisville, Kentucky, 40202, United States
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University of Missouri - Ellis Fischel Cancer Center
Columbia, Missouri, 65212, United States
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University of Utah
Salt Lake City, Utah, 84112, United States
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Vancouver Coastal Health Research Institution (VCHRI)
Vancouver, British Columbia, V5Z 1M9, Canada
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Weill Cornell Medicine-New York Presbyterian Hospital
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple scan and blood test outsmart liver cancer?
- Could a vaccine help fight Hard-to-Treat cancers?
- Could a tailored diet before surgery boost liver cancer recovery?
- Can a new PET tracer light up hidden cancers?
- A new imaging agent could tell doctors which liver cancers will resist immunotherapy
- A new test could reveal how radiation affects the liver